Tadalafil 5 mg (Cialis): treating ED and BPH by muscle relaxation.
tadalafil at 5 mg is mainly used for the treatment of erectile dysfunction (ED) in men.
1. Mechanism of action
-Tadalafil inhibits the enzyme phosphodiesterase-5 (PDE-5). This enzyme is responsible for the degradation of a chemical compound called cyclic monophosphate guanosin (cGMP) in the cavernous tissue of the penis. By inhibiting PDE-5, tadalafil allows cGMP levels to remain high.
-increased cGMP causes relaxation of smooth muscles in cavernous tissue, allowing greater blood flow to the penis, facilitating erection.
2. Benefits of erectile dysfunction
-help men get and maintain an erection suitable for satisfactory sexual activity.
-unlike some other treatments, tadalafil has a relatively prolonged action. At a dose of 5 mg, it can have an effect over a period of up to about 36 hours, giving patients greater flexibility in terms of planning sexual activity compared to some drugs that have a shorter effect.
In addition, tadalafil at 5 mg is also being investigated and in some cases used in the treatment of other disorders related to blood circulation in the male urinary tract, such as benign prostate hypertrophy (HBP), as it can improve urinary symptoms associated with this disorder by relaxing the muscles of the urinary tract. However, it should be used under medical supervision, as it may have adverse effects and contraindications.