CIALIS 20MG: Unraveling the Features and Benefits
Gui í a de Salud Masculina
Cialis (tadalafil) 20mg is a drug used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH)-related symptoms. Here is some information:
I. Pharmacological action
Mechanism of action on erectile dysfunction
Tadalafil is a phosphodiesterase 5 (PDE5) inhibitor. During sexual stimulation, nitric oxide (NO) is released from neuronal terminals in the penile sponge. NO activates guanylate cyclase and increases the level of cyclic guanosine monophosphate (cGMP), which leads to relaxation of corpus cavernosum smooth muscle, blood flow into penile tissue and erection.
PDE5 breaks down cGMP and reduces its concentration, leading to erection regression. Tadalafil inhibits the activity of PDE5, reduces the degradation of cGMP, maintains the level of cGMP in corpus cavernosum smooth muscle cells, and contributes to penile erection and erection.
Mechanism of action on benign prostatic hyperplasia
Tadalafil can improve lower urinary tract symptoms such as dysuria, frequent urination and urgent urination by inhibiting PDE5 and relaxing the smooth muscle of prostate and bladder neck, which helps to increase urinary flow rate and relieve urinary tract obstruction caused by benign prostatic hyperplasia.
II. Usage
Usage
Tadalafil tablets are usually taken orally when needed and are recommended to be taken about 30 minutes to 1 hour before sexual activity when used in the treatment of erectile dysfunction. However, the effect of tadalafil can last up to 36 hours, so sexual stimulation may trigger an erectile response within this time frame.
-for the long-term treatment of benign prostatic hyperplasia, it is generally taken according to the daily fixed dose regimen.
Matters needing attention
-do not drink alcohol when taking tadalafil. Alcohol may increase the side effects of the drug, such as hypotension and dizziness.
-avoid using in conjunction with certain drugs, such as organic nitrates (such as nitroglycerin), as combined use may lead to severe hypotension.
Third, adverse reactions
Common adverse reactions
Headache is a common side effect, which may be related to the vasodilating effect of drugs.
-facial flushing, which is due to the feeling of redness and fever caused by vasodilation.
-indigestion, including stomach discomfort, flatulence, nausea and other symptoms.
-back pain, muscle pain, etc., but these symptoms are usually mild to moderate and may gradually disappear after withdrawal.
Rare but serious adverse reactions
-sudden vision loss or loss, although this is very rare, if you have vision problems while taking tadalafil, you should stop using it immediately and seek medical attention.
-there are also very few reports of hearing loss or loss, which need to be paid attention to.
IV. Contraindications
-it is prohibited for people with non-ingredient allergies in Tadala.
-patients who are using any form of organic nitrates (such as nitroglycerin, isosorbide mononitrate, etc.), as simultaneous use can lead to severe hypotension and life-threatening.
-it is not suitable for women, children and young people under the age of 18, as tadalafil is mainly used in the treatment of erectile dysfunction and benign prostatic hyperplasia in men, and the safety and efficacy have not been determined in other populations.
The use of tadalafil 20mg should be carried out under the guidance of a doctor, and patients should consult a doctor in time if there is any discomfort or abnormality in the course of use.